Biofilms have been around for at least 3.3 billion years forming on every wet or moist surface in the world.
They are made up of multiple types of bacteria
When bacteria exist in biofilm they can become 1000 times more resistant to antibiotics
The biofilm residents talk to each to coordinate the behavior of the entire community
Biofilm is a bacterial fortress in a hostile environment
These biofilms aggravate lung tissue damage
Therapeutic failure when treating drug resistant infections is often associated with the existence of a biofilm. These biofilms are extremely difficult or even impossible to eradicate if the normal host defenses are compromised. Biofilm-associated drug resistance mechanisms ensure the survival and persistence of infections for years despite intensive antibiotic treatment or functional host defenses. Well-developed mature biofilms can thwart many antibiotic classes by intrinsic or adaptive resistances.